The Significance of Excepient...a Review
Abstract
Significance of Excipients………A Review
Vd. Sujata Ramteke (PG scholar), Guide Vd. Avinash Chougule, HOD – Vd. Mahesh Inamdar, Department of Ras-shastra & Bhaishajya Kalpana, Shri Annasaheb Dange Ayurvedic Medical College, Ashta, (Dist) Sangli
Abstract
An excipient is a non-therapeutic substance and active ingredients which are essentially included in the development and designing of drug products. It is used for bulking up solid formulations and long-term stabilization. Excipient plays an important role in formulation that decide dosage form as well as Pharmacokinetics and pharmacodynamics of medicine. It also improves dissolution rate and bioavailability of the drug and also improve bulkiness, disintegration. Excipients can initiate, participate or propagate in chemical or physical interactions with drug compounds. Excipients as like other active pharmaceutical ingredients also need to be standardize and stabilize. Specific excipients are best suited for a particular dosage form so proper selection of the excipients is very much important as various interactions take place during its course of stay in formulation.
Keywords: Excipient, Formulation, bioavailability, pharmaceutical ingredients.
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