Randomized open control clinical study to evaluate the efficacy of “Amalakyadiloha” Orally with comparison to “Amlapittantakloha” in the management of Urdhwaga Amlapitta in age group from 18 to 55 years
Keywords:
Amalakyadiloha, Amlapittantakloha, GERD (Gastro Esophageal Reflux Disease)Abstract
Aacharya kashyap has first of all mentioned the disease amlapitta in separate chapter. Aacharya Kashyap has also analyzed Amlapitta based on dosha; however, Kashyap held that Amlapitta is created by vatiation of tridosha caused mandagni leading to vidhagdajirna, which in turn manifests as Amlapitta.Madhavkar has given its classification on the basis of dosha gati. According to Aacharya Charak, manas bhava like chinta (worry), shok (grief), krodha (rage) and bhaya (fear) cause the agni to vatiate, which in turn aggravates the illness. In Charak Samhita, Amlapitta has not been described as a disease. He has mentioned that when amavisha is directly mixed with pitta and Amlapitta will developed. Total 60 patients of Amlapitta selected randomly which is then divided into two equal Groups i.e. 30 patients in each group. Giving intervention by ‘ Amalakyadiloha ’ orally locally for group A and ‘Amlapittantakloha’ locally for group B for 45 days treatment and follow up taken for post therapy 45 days. Analysis of all patients were done and after that Result and conclusion were drawn. All symptoms were significantly reduced in Group A and Group B (Wilcoxon Signed Ranks test; P<0.05).In Trial group (Amalakyadiloha) average % relief was 66.79%. In Control Group (Amlapittantakloha) average % relief was 70.12%. On the basis of overall percent relief, Oral administration of Amalakyadiloha is less effective than Amlapittantakloha in the management of Urdhwaga Amlapitta to reduce Tikta-amla udgar, Hrit Kantha daha, Utklesha, Chardi, Aruchi, Udarshool and Gaurav.
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