Role of lifestyle as a modifiable risk factor in the development of alzheimer’s disease- a literary review.

Abstract

Alzheimer's disease is a progressive neurodegenerative condition, primarily affecting the elderly, that impacts memory, cognitive abilities, and behavior. The challenges posed by this disease not only deteriorate personal health but also place a significant strain on public health systems. Evaluating changeable risk factors associated with Alzheimer’s is essential for preventing or postponing the development of the disease. Objective- To evaluate the association of lifestyle in the development Alzheimer’s disease. Methodology- Medial literature related to Alzheimer’s disease, medical journals, e-publications as well as Ayurveda classics been scrutinized to review interrelation of lifestyle and Alzheimer’s disease. Results- Evidential studies entangles cardiovascular, cerebrovascular disease, Diabetes, undernourished diet, dormant lifestyle as predispositions for AD. Enhancing lifestyle choices can influence the prevalence of Alzheimer’s disease both directly—by consuming foods rich in antioxidants and low in cholesterol—and indirectly, by reducing other risk factors like high blood pressure, elevated cholesterol levels, and diabetes. Adherence to a healthy lifestyle may affect AD directly or indirectly by preventing these diseases. Conclusion- However, there is no precise evidence yet of the role of lifestyle behaviours and AD. Risk factors like hypertension, high cholesterol, low cognitive activities, and diabetes, are associated with subsequent development of AD can be modified by adaption of healthy lifestyle. Although current scientific documentation is inadequate, substantial evidence suggests that, a combination of healthful diet steps and regular physical exercise may reduce the risk of developing Alzheimer’s disease.

KEYWORDS- Alzheimer’s disease, Ayurveda, Lifestyle, Risk Factor.