Diseases emanating from GIT form a considerable part of practice in India and abroad. Starting from ancient time to the modern era, Grahani Dosha has remained a fore runner but has also behaved like the fountain head of many GIT ailments. Grahani Dosha is associated with digestive problem and prevalence of Grahani increase in current scenario due to the bad dietary habits, irregular lifestyle, stress and environmental condition. As per Ayurveda, Agni is maintained properly then the individual will be free from many diseases. If it gets vitiated then individual becomes host for ample number of disease, among them Grahani is the most prevalent disease in these days. The cardinal features of Grahani explained in the classical text book of Ayurveda, have at most similarities with clinical feature of celiac disease explained in western medicine. Celiac disease is also termed as celiac sprue or gluten sensitive enteropathy. It is an autoimmune digestive disorder. According to Ayurveda, CD can be related with annavaha srotas dushti. Celiac disease can be correlated with grahani roga. Agnimandya (low digestive fire) result in formation of Aama and the disease manifests. Piccha basti is indicated in Jeerna grahani and Jeerna atisara avastha by charaka and vagbhata. Piccha basti reduces inflammation due to its grahi, Deepana dravya and picchila guna. it also improve the function of apana vata. A use of piccha basti, Deepana, pachana dravya, and along with the dietary modifications gives maximum relief in Celiac disease.
KEYWORDS: Piccha basti, Celiac Disease, Grahani, Gluten sensitivity.