"To Evaluate the effect of Trikatu on the experimental model of high fat diet induced Hyperlipidemia."

Authors

  • Bomble Rajashri

Keywords:

Trikatu,   HFD,   hyperlipidemia,  Lipids

Abstract

Luxurious life and sedentary habits body fats along with cholesterols are increasing in the body,  which invites the disorders like hypertension,  heart diseases,  and hyperlipedemia. Hyperlipidemia is a condition in which the levels of lipoproteins,  i.e. cholesterols,  triglycerides or both are raided in plasma to the extent that it may have adverse effect in health leading to life expectancy.. The Trikatu churna makes this traditional drug more stable for long term storage and hence, .easier to prepare. The Trikatu churna is a reputed drug mentioned in the ancient books of Ayurveda used for the treatment of various diseases. The experimental study was carried out for 42 days. In which for first 21 days the obesity was induced by creating high fat induced obesity experimental model of wistar rats male,  which was further treated for next 21 days with three different test drug dosage  of Trikatu  (A),  of 90mg/kg.,  Trikatu  (B) of 180mg/kg and Trikatu (C) of 270mg/kg were used. For obesity induction Vanaspati Ghee  (Dalda) and coconut oil  (Parachute) was used in which daily pellets were soaked overnight .The Lipids were recorded,  the blood samples were collected on 0,  21 and 42 days respectively. Standard Drug Atorvastatin was used . The blood samples were send for histopathological results and the stastistical analysis was done with Annova method. Obesity was induced till day'21 and again was reduced satisfactorily by Trikatu group (A) and group  (C ) showed maximum satisfactory results with histopathological changes.

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Published

2020-10-12

How to Cite

Bomble Rajashri. (2020). "To Evaluate the effect of Trikatu on the experimental model of high fat diet induced Hyperlipidemia.". Ayurline: International Journal of Research in Indian Medicine, 4(05). Retrieved from https://ayurline.in/index.php/ayurline/article/view/441

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Section

Original Research Articles