The Role of Langhana and amapachana in rare autoimmune disease takayashu arteritis -a case study

Authors

  • NEENA DAMLE ASSISTANT PROFESSOR
  • ARCHANA RAJARAM GHARGE PROFESSOR

DOI:

https://doi.org/10.52482/ayurline.v10i02.1048

Keywords:

Keywords: Takayasu’s arteritis ,Panchatiktakwath, Rasapachak, Triphala

Abstract

Introduction -Takayasu’s arteritis is a chronic vasculitis of medium and large vessels. The most involved vessel are the Carotid Artery, Aorta and other major branches. 

Background -A 31-year-old woman who presented with history of syncope and dizziness with thickened walls of carotid artery in Magnetic Resonance Imaging angiogram finding. 2 years back she had 3 episodes of sudden syncope and unconsciousness and visited KEM hospital Parel, Mumbai. Takayashu arteritis was diagnosed at KEM hospital and they started her Prednisolone 40 mg/day orally, Methotrexate 15 mg/week, Aspirin 75 mg/day, and folic acid 5 mg/week. After discharge a maintenance dose of Methotrexate 10 mg/week and 8 mg/day of Methylprednisolone along with Aspirin 75 mg/day, and folic acid 5 mg/week orally was continued .

Case Report : Patient visited D.Y. Patil Ayurvedic hospital one year before with complains of giddiness and myalgia. Her inflammatory markers ESR was 90 mm/hr and CRP was 30mg/L. At D.Y.Patil Ayurvedic Hospital after Rogi Roga pariksha I started add on Ayurvedic medicines Panchatiktakwathchurna 3 gms BD morning and evening , Maha Manjishthadighanavati 2 tds ,Triphalachurna 5 gm hs ,Rasapachakvati 2 tds. Every day 15 hours fasting was advised as pathya daily 45 min walking was advised.

Results- After 11 months she started showing symptomatic relief and also 50% reduction in her inflammatory marker  ESR and CRP levels turn normal with Ayurvedic medicines.

Conclusion :The case study shows that Takayasu arteritis (TA) was managed with Langhanaand AamapachakaAyurvedic medication with satisfactory outcome.

Author Biography

ARCHANA RAJARAM GHARGE, PROFESSOR

PROFESSOR, ROGNIDAN AND VIKRUTI VIGYAN DEPARTMENT, DR.G.D.POL FOUNDATION YMT AYURVEDIC MEDICAL COLLEGE, KHARGHAR

References

1.Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol. 2002 Jul;55(7):481-6. [PMC free article] [PubMed]

2.Arnaud L, Haroche J, Mathian A, Gorochov G, Amoura Z. Pathogenesis of Takayasu's arteritis: a 2011 update. Autoimmun Rev. 2011 Nov;11(1):61-7. [PubMed]

3.Mason JC. Surgical intervention and its role in Takayasu arteritis. Best Pract Res Clin Rheumatol. 2018 Feb;32(1):112-124. [PubMed]

4.Comarmond C, Biard L, Lambert M, Mekinian A, Ferfar Y, Kahn JE, Benhamou Y, Chiche L, Koskas F, Cluzel P, Hachulla E, Messas E, Resche-Rigon M, Cacoub P, Mirault T, Saadoun D., French Takayasu Network. Long-Term Outcomes and Prognostic Factors of Complications in Takayasu Arteritis: A Multicenter Study of 318 Patients. Circulation. 2017 Sep 19;136(12):1114-1122. [PubMed]

5.Shah B, Chhetri R. Malignant Ischemic Stroke in a Young Female: A Rare Primary Manifestation of Takayasu Arteritis. Case Rep Neurol Med. 2019;2019:7942825. [PMC free article] [PubMed]

6.Vargas-Hitos JA, Jiménez-Jáimez J, Molina Navarro E, Salmerón Ruiz A, López Milena G, Jiménez-Alonso J. Takayasu arteritis, malignant hypertension and severe left ventricular hypertrophy. Int J Rheum Dis. 2019 May;22(5):951-955. [PubMed]

7.Kwon OC, Oh JS, Park MC, Hong S, Lee CK, Yoo B, Kim YG. Statins reduce relapse rate in Takayasu arteritis. Int J Cardiol. 2019 Jul 15;287:111-115. [PubMed]

8.Chauhan R, Luthra A, Mahajan S. Takayasu Arteritis with Cerebral Hypoperfusion: An Unusual Case. J Neurosci Rural Pract. 2019 Jan-Mar;10(1):170-171. [PMC free article] [PubMed]

9.Pandey G, editor. Charaka Samhita of Agnivesha, Sutra Sthana C.Su.chap.18 shloka 44. Ver. 38-42. 1st ed. Varanasi: Chaukhamba Sanskrit Sansthana; 2006.

10.Pandey G, editor. Charaka Samhita of Agnivesha, Chikitsa Sthana .chap.30 shloka 291-292) Ver. 38-42. 1st ed. Varanasi: Chaukhamba Sanskrit Sansthana; 2006.

REFERENCES

1.Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol. 2002 Jul;55(7):481-6. [PMC free article] [PubMed]

2.Arnaud L, Haroche J, Mathian A, Gorochov G, Amoura Z. Pathogenesis of Takayasu's arteritis: a 2011 update. Autoimmun Rev. 2011 Nov;11(1):61-7. [PubMed]

3.Mason JC. Surgical intervention and its role in Takayasu arteritis. Best Pract Res Clin Rheumatol. 2018 Feb;32(1):112-124. [PubMed]

4.Comarmond C, Biard L, Lambert M, Mekinian A, Ferfar Y, Kahn JE, Benhamou Y, Chiche L, Koskas F, Cluzel P, Hachulla E, Messas E, Resche-Rigon M, Cacoub P, Mirault T, Saadoun D., French Takayasu Network. Long-Term Outcomes and Prognostic Factors of Complications in Takayasu Arteritis: A Multicenter Study of 318 Patients. Circulation. 2017 Sep 19;136(12):1114-1122. [PubMed]

5.Shah B, Chhetri R. Malignant Ischemic Stroke in a Young Female: A Rare Primary Manifestation of Takayasu Arteritis. Case Rep Neurol Med. 2019;2019:7942825. [PMC free article] [PubMed]

6.Vargas-Hitos JA, Jiménez-Jáimez J, Molina Navarro E, Salmerón Ruiz A, López Milena G, Jiménez-Alonso J. Takayasu arteritis, malignant hypertension and severe left ventricular hypertrophy. Int J Rheum Dis. 2019 May;22(5):951-955. [PubMed]

7.Kwon OC, Oh JS, Park MC, Hong S, Lee CK, Yoo B, Kim YG. Statins reduce relapse rate in Takayasu arteritis. Int J Cardiol. 2019 Jul 15;287:111-115. [PubMed]

8.Chauhan R, Luthra A, Mahajan S. Takayasu Arteritis with Cerebral Hypoperfusion: An Unusual Case. J Neurosci Rural Pract. 2019 Jan-Mar;10(1):170-171. [PMC free article] [PubMed]

9.Pandey G, editor. Charaka Samhita of Agnivesha, Sutra Sthana C.Su.chap.18 shloka 44. Ver. 38-42. 1st ed. Varanasi: Chaukhamba Sanskrit Sansthana; 2006.

10.Pandey G, editor. Charaka Samhita of Agnivesha, Chikitsa Sthana .chap.30 shloka 291-292) Ver. 38-42. 1st ed. Varanasi: Chaukhamba Sanskrit Sansthana; 2006.

REFERENCES

1.Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol. 2002 Jul;55(7):481-6. [PMC free article] [PubMed]

2.Arnaud L, Haroche J, Mathian A, Gorochov G, Amoura Z. Pathogenesis of Takayasu's arteritis: a 2011 update. Autoimmun Rev. 2011 Nov;11(1):61-7. [PubMed]

3.Mason JC. Surgical intervention and its role in Takayasu arteritis. Best Pract Res Clin Rheumatol. 2018 Feb;32(1):112-124. [PubMed]

4.Comarmond C, Biard L, Lambert M, Mekinian A, Ferfar Y, Kahn JE, Benhamou Y, Chiche L, Koskas F, Cluzel P, Hachulla E, Messas E, Resche-Rigon M, Cacoub P, Mirault T, Saadoun D., French Takayasu Network. Long-Term Outcomes and Prognostic Factors of Complications in Takayasu Arteritis: A Multicenter Study of 318 Patients. Circulation. 2017 Sep 19;136(12):1114-1122. [PubMed]

5.Shah B, Chhetri R. Malignant Ischemic Stroke in a Young Female: A Rare Primary Manifestation of Takayasu Arteritis. Case Rep Neurol Med. 2019;2019:7942825. [PMC free article] [PubMed]

6.Vargas-Hitos JA, Jiménez-Jáimez J, Molina Navarro E, Salmerón Ruiz A, López Milena G, Jiménez-Alonso J. Takayasu arteritis, malignant hypertension and severe left ventricular hypertrophy. Int J Rheum Dis. 2019 May;22(5):951-955. [PubMed]

7.Kwon OC, Oh JS, Park MC, Hong S, Lee CK, Yoo B, Kim YG. Statins reduce relapse rate in Takayasu arteritis. Int J Cardiol. 2019 Jul 15;287:111-115. [PubMed]

8.Chauhan R, Luthra A, Mahajan S. Takayasu Arteritis with Cerebral Hypoperfusion: An Unusual Case. J Neurosci Rural Pract. 2019 Jan-Mar;10(1):170-171. [PMC free article] [PubMed]

9.Pandey G, editor. Charaka Samhita of Agnivesha, Sutra Sthana C.Su.chap.18 shloka 44. Ver. 38-42. 1st ed. Varanasi: Chaukhamba Sanskrit Sansthana; 2006.

10.Pandey G, editor. Charaka Samhita of Agnivesha, Chikitsa Sthana .chap.30 shloka 291-292) Ver. 38-42. 1st ed. Varanasi: Chaukhamba Sanskrit Sansthana; 2006.

REFERENCES

1.Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol. 2002 Jul;55(7):481-6. [PMC free article] [PubMed]

2.Arnaud L, Haroche J, Mathian A, Gorochov G, Amoura Z. Pathogenesis of Takayasu's arteritis: a 2011 update. Autoimmun Rev. 2011 Nov;11(1):61-7. [PubMed]

3.Mason JC. Surgical intervention and its role in Takayasu arteritis. Best Pract Res Clin Rheumatol. 2018 Feb;32(1):112-124. [PubMed]

4.Comarmond C, Biard L, Lambert M, Mekinian A, Ferfar Y, Kahn JE, Benhamou Y, Chiche L, Koskas F, Cluzel P, Hachulla E, Messas E, Resche-Rigon M, Cacoub P, Mirault T, Saadoun D., French Takayasu Network. Long-Term Outcomes and Prognostic Factors of Complications in Takayasu Arteritis: A Multicenter Study of 318 Patients. Circulation. 2017 Sep 19;136(12):1114-1122. [PubMed]

5.Shah B, Chhetri R. Malignant Ischemic Stroke in a Young Female: A Rare Primary Manifestation of Takayasu Arteritis. Case Rep Neurol Med. 2019;2019:7942825. [PMC free article] [PubMed]

6.Vargas-Hitos JA, Jiménez-Jáimez J, Molina Navarro E, Salmerón Ruiz A, López Milena G, Jiménez-Alonso J. Takayasu arteritis, malignant hypertension and severe left ventricular hypertrophy. Int J Rheum Dis. 2019 May;22(5):951-955. [PubMed]

7.Kwon OC, Oh JS, Park MC, Hong S, Lee CK, Yoo B, Kim YG. Statins reduce relapse rate in Takayasu arteritis. Int J Cardiol. 2019 Jul 15;287:111-115. [PubMed]

8.Chauhan R, Luthra A, Mahajan S. Takayasu Arteritis with Cerebral Hypoperfusion: An Unusual Case. J Neurosci Rural Pract. 2019 Jan-Mar;10(1):170-171. [PMC free article] [PubMed]

9.Pandey G, editor. Charaka Samhita of Agnivesha, Sutra Sthana C.Su.chap.18 shloka 44. Ver. 38-42. 1st ed. Varanasi: Chaukhamba Sanskrit Sansthana; 2006.

10.Pandey G, editor. Charaka Samhita of Agnivesha, Chikitsa Sthana .chap.30 shloka 291-292) Ver. 38-42. 1st ed. Varanasi: Chaukhamba Sanskrit Sansthana; 2006.

Published

16-03-2026

How to Cite

NEENA DAMLE, & ARCHANA RAJARAM GHARGE. (2026). The Role of Langhana and amapachana in rare autoimmune disease takayashu arteritis -a case study. Ayurline: International Journal of Research in Indian Medicine, 10(02). https://doi.org/10.52482/ayurline.v10i02.1048

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