The Role of Langhana and amapachana in rare autoimmune disease takayashu arteritis -a case study

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NEENA DAMLE
ARCHANA RAJARAM GHARGE

Abstract

Introduction -Takayasu’s arteritis is a chronic vasculitis of medium and large vessels. The most involved vessel are the Carotid Artery, Aorta and other major branches. 


Background -A 31-year-old woman who presented with history of syncope and dizziness with thickened walls of carotid artery in Magnetic Resonance Imaging angiogram finding. 2 years back she had 3 episodes of sudden syncope and unconsciousness and visited KEM hospital Parel, Mumbai. Takayashu arteritis was diagnosed at KEM hospital and they started her Prednisolone 40 mg/day orally, Methotrexate 15 mg/week, Aspirin 75 mg/day, and folic acid 5 mg/week. After discharge a maintenance dose of Methotrexate 10 mg/week and 8 mg/day of Methylprednisolone along with Aspirin 75 mg/day, and folic acid 5 mg/week orally was continued .


Case Report : Patient visited D.Y. Patil Ayurvedic hospital one year before with complains of giddiness and myalgia. Her inflammatory markers ESR was 90 mm/hr and CRP was 30mg/L. At D.Y.Patil Ayurvedic Hospital after Rogi Roga pariksha I started add on Ayurvedic medicines Panchatiktakwathchurna 3 gms BD morning and evening , Maha Manjishthadighanavati 2 tds ,Triphalachurna 5 gm hs ,Rasapachakvati 2 tds. Every day 15 hours fasting was advised as pathya daily 45 min walking was advised.


Results- After 11 months she started showing symptomatic relief and also 50% reduction in her inflammatory marker  ESR and CRP levels turn normal with Ayurvedic medicines.


Conclusion :The case study shows that Takayasu arteritis (TA) was managed with Langhanaand AamapachakaAyurvedic medication with satisfactory outcome.

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Author Biography

ARCHANA RAJARAM GHARGE, PROFESSOR

PROFESSOR, ROGNIDAN AND VIKRUTI VIGYAN DEPARTMENT, DR.G.D.POL FOUNDATION YMT AYURVEDIC MEDICAL COLLEGE, KHARGHAR

How to Cite
NEENA DAMLE, & ARCHANA RAJARAM GHARGE. (2026). The Role of Langhana and amapachana in rare autoimmune disease takayashu arteritis -a case study. Ayurline: International Journal of Research in Indian Medicine, 10(02). Retrieved from https://ayurline.in/index.php/ayurline/article/view/1048

References

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  2. 2.Arnaud L, Haroche J, Mathian A, Gorochov G, Amoura Z. Pathogenesis of Takayasu's arteritis: a 2011 update. Autoimmun Rev. 2011 Nov;11(1):61-7. [PubMed]
  3. 3.Mason JC. Surgical intervention and its role in Takayasu arteritis. Best Pract Res Clin Rheumatol. 2018 Feb;32(1):112-124. [PubMed]
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  5. 5.Shah B, Chhetri R. Malignant Ischemic Stroke in a Young Female: A Rare Primary Manifestation of Takayasu Arteritis. Case Rep Neurol Med. 2019;2019:7942825. [PMC free article] [PubMed]
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  7. 7.Kwon OC, Oh JS, Park MC, Hong S, Lee CK, Yoo B, Kim YG. Statins reduce relapse rate in Takayasu arteritis. Int J Cardiol. 2019 Jul 15;287:111-115. [PubMed]
  8. 8.Chauhan R, Luthra A, Mahajan S. Takayasu Arteritis with Cerebral Hypoperfusion: An Unusual Case. J Neurosci Rural Pract. 2019 Jan-Mar;10(1):170-171. [PMC free article] [PubMed]
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  15. 4.Comarmond C, Biard L, Lambert M, Mekinian A, Ferfar Y, Kahn JE, Benhamou Y, Chiche L, Koskas F, Cluzel P, Hachulla E, Messas E, Resche-Rigon M, Cacoub P, Mirault T, Saadoun D., French Takayasu Network. Long-Term Outcomes and Prognostic Factors of Complications in Takayasu Arteritis: A Multicenter Study of 318 Patients. Circulation. 2017 Sep 19;136(12):1114-1122. [PubMed]
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  17. 6.Vargas-Hitos JA, Jiménez-Jáimez J, Molina Navarro E, Salmerón Ruiz A, López Milena G, Jiménez-Alonso J. Takayasu arteritis, malignant hypertension and severe left ventricular hypertrophy. Int J Rheum Dis. 2019 May;22(5):951-955. [PubMed]
  18. 7.Kwon OC, Oh JS, Park MC, Hong S, Lee CK, Yoo B, Kim YG. Statins reduce relapse rate in Takayasu arteritis. Int J Cardiol. 2019 Jul 15;287:111-115. [PubMed]
  19. 8.Chauhan R, Luthra A, Mahajan S. Takayasu Arteritis with Cerebral Hypoperfusion: An Unusual Case. J Neurosci Rural Pract. 2019 Jan-Mar;10(1):170-171. [PMC free article] [PubMed]
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  23. 1.Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol. 2002 Jul;55(7):481-6. [PMC free article] [PubMed]
  24. 2.Arnaud L, Haroche J, Mathian A, Gorochov G, Amoura Z. Pathogenesis of Takayasu's arteritis: a 2011 update. Autoimmun Rev. 2011 Nov;11(1):61-7. [PubMed]
  25. 3.Mason JC. Surgical intervention and its role in Takayasu arteritis. Best Pract Res Clin Rheumatol. 2018 Feb;32(1):112-124. [PubMed]
  26. 4.Comarmond C, Biard L, Lambert M, Mekinian A, Ferfar Y, Kahn JE, Benhamou Y, Chiche L, Koskas F, Cluzel P, Hachulla E, Messas E, Resche-Rigon M, Cacoub P, Mirault T, Saadoun D., French Takayasu Network. Long-Term Outcomes and Prognostic Factors of Complications in Takayasu Arteritis: A Multicenter Study of 318 Patients. Circulation. 2017 Sep 19;136(12):1114-1122. [PubMed]
  27. 5.Shah B, Chhetri R. Malignant Ischemic Stroke in a Young Female: A Rare Primary Manifestation of Takayasu Arteritis. Case Rep Neurol Med. 2019;2019:7942825. [PMC free article] [PubMed]
  28. 6.Vargas-Hitos JA, Jiménez-Jáimez J, Molina Navarro E, Salmerón Ruiz A, López Milena G, Jiménez-Alonso J. Takayasu arteritis, malignant hypertension and severe left ventricular hypertrophy. Int J Rheum Dis. 2019 May;22(5):951-955. [PubMed]
  29. 7.Kwon OC, Oh JS, Park MC, Hong S, Lee CK, Yoo B, Kim YG. Statins reduce relapse rate in Takayasu arteritis. Int J Cardiol. 2019 Jul 15;287:111-115. [PubMed]
  30. 8.Chauhan R, Luthra A, Mahajan S. Takayasu Arteritis with Cerebral Hypoperfusion: An Unusual Case. J Neurosci Rural Pract. 2019 Jan-Mar;10(1):170-171. [PMC free article] [PubMed]
  31. 9.Pandey G, editor. Charaka Samhita of Agnivesha, Sutra Sthana C.Su.chap.18 shloka 44. Ver. 38-42. 1st ed. Varanasi: Chaukhamba Sanskrit Sansthana; 2006.
  32. 10.Pandey G, editor. Charaka Samhita of Agnivesha, Chikitsa Sthana .chap.30 shloka 291-292) Ver. 38-42. 1st ed. Varanasi: Chaukhamba Sanskrit Sansthana; 2006.
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  35. 2.Arnaud L, Haroche J, Mathian A, Gorochov G, Amoura Z. Pathogenesis of Takayasu's arteritis: a 2011 update. Autoimmun Rev. 2011 Nov;11(1):61-7. [PubMed]
  36. 3.Mason JC. Surgical intervention and its role in Takayasu arteritis. Best Pract Res Clin Rheumatol. 2018 Feb;32(1):112-124. [PubMed]
  37. 4.Comarmond C, Biard L, Lambert M, Mekinian A, Ferfar Y, Kahn JE, Benhamou Y, Chiche L, Koskas F, Cluzel P, Hachulla E, Messas E, Resche-Rigon M, Cacoub P, Mirault T, Saadoun D., French Takayasu Network. Long-Term Outcomes and Prognostic Factors of Complications in Takayasu Arteritis: A Multicenter Study of 318 Patients. Circulation. 2017 Sep 19;136(12):1114-1122. [PubMed]
  38. 5.Shah B, Chhetri R. Malignant Ischemic Stroke in a Young Female: A Rare Primary Manifestation of Takayasu Arteritis. Case Rep Neurol Med. 2019;2019:7942825. [PMC free article] [PubMed]
  39. 6.Vargas-Hitos JA, Jiménez-Jáimez J, Molina Navarro E, Salmerón Ruiz A, López Milena G, Jiménez-Alonso J. Takayasu arteritis, malignant hypertension and severe left ventricular hypertrophy. Int J Rheum Dis. 2019 May;22(5):951-955. [PubMed]
  40. 7.Kwon OC, Oh JS, Park MC, Hong S, Lee CK, Yoo B, Kim YG. Statins reduce relapse rate in Takayasu arteritis. Int J Cardiol. 2019 Jul 15;287:111-115. [PubMed]
  41. 8.Chauhan R, Luthra A, Mahajan S. Takayasu Arteritis with Cerebral Hypoperfusion: An Unusual Case. J Neurosci Rural Pract. 2019 Jan-Mar;10(1):170-171. [PMC free article] [PubMed]
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